The capacity of an organism to regenerate depends on cell dedifferentiation followed by proliferation. Mammals, in general, have limited regenerative capacity. Now, a team of researchers at the Salk ...

A team led by researchers has discovered that a group of cells located in the skin and other areas of the body, called neural crest stem cells, are the source of reprogrammed neurons found by other ...

Both Natural and Experimental Processes Stand to Benefit from Greater Understanding of Nongenetic Factors The mechanisms that ensure that cells from multicellular organisms are genetically homogenous, ...

Scientists have observed signs of rejuvenation in the pancreas, liver, spleen, and blood of mice after applying one cycle of cell reprogramming. To achieve this, the researchers have characterized ...

Scientists reverse eye cell aging with ER-100 gene therapy that reprograms retinal neurons to younger states, offering hope ...

Researchers from Japan reveal that they may just have found a way to repair cardiac damage in patients suffering from chronic heart attack and heart failure. In a study published in Circulation, ...

Studies on diseases that affect the human brain are usually based on animal models which cannot reproduce the complexity of human neuropathies. Therefore, these methodologies often fail when applied ...

Billions of dollars are pouring into longevity startups as a growing body of research shows that aging might not be as inevitable as we assumed. Now, a startup claims to have reached a major milestone ...

For all they do for us, our hearts aren't very good at repairing themselves. So when a person suffers a heart attack, their blood pump is left with a large amount of scar tissue, which can impede the ...

Modulation of a single amino acid in the reprogramming factor Kruppel-like factor 4 (KLF4) has been demonstrated to markedly improve natural transcription factor function and to result in faster and ...

The first clinical attempt to make human beings biologically younger is no longer a thought experiment. A small gene therapy ...