A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that ...

Bowel cancer cells have the ability to regulate their growth using a genetic on-off switch to maximize their chances of survival, a phenomenon that's been observed for the first time by researchers at ...

Cancer’s strongest gene switches push DNA into damaging overdrive, creating repeated breaks and repairs that may fuel tumor ...

While the genes involved can differ, this example illustrates how most cancers arise. Accumulated DNA mutations, acquired either over time (ageing naturally leads to some DNA mistakes) or from ...

A study explains how broken DNA during cell division can trigger chromoanasynthesis when two repair pathways combine, causing ...

An analysis of pre-treatment tumor specimens from 105 patients with localized muscle-invasive bladder cancer found that the presence of a mutation in any one of three genes, all known to be involved ...

Impact of Genomic Alterations on Efficacy of Trastuzumab Deruxtecan Against Human Epidermal Growth Factor Receptor-2–Positive Advanced Gastric Cancer This was a prospective, cross-sectional, ...

Researchers at Cardiff University have uncovered how a particularly severe form of DNA damage arises—shedding new light on ...

Dr. Elizabeth R. Plimack, MD, MS, FASCO, is lead author of a paper in European Urology reporting on an analysis of specimens from the SWOG S1314 trial in localized muscle-invasive bladder cancer that ...