Mutations are the raw ingredient of evolution, providing variation that sometimes makes an organism more successful in its environment. But most mutations are expected to be neutral and have no impact ...

"Because many biological conclusions rely on the presumption that synonymous mutations are neutral, its invalidation has broad implications. For example, synonymous mutations are generally ignored in ...

Since the genetic code was solved in the 1960s, synonymous mutations have been generally thought to be benign. We now show that this belief is false. Because many biological conclusions rely on the ...