Proteins adopt unstable, high-energy states that exist for fractions of a second but can have key biological roles. A new method of determining high-resolution structures of such states using a form ...

To function correctly, cellular proteins depend not only on their complex tertiary and quaternary structures, but also on their proximity to and interactions with other molecules participating in the ...

On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...

Last year DeepMind put forward a compelling a solution to a 50-year-old science problem, demonstrating how its AlphaFold AI could predict the 3D structures of unique proteins, laying the groundwork ...

DeepMind is releasing a free expanded database with its predictions of the structure of nearly every protein known to science, the company, a subsidiary of Google parent Alphabet, announced today.

Chemically, proteins are just a long string of amino acids. Their amazing properties come about because that chain can fold up into a complex, three-dimensional shape. So understanding the rules that ...

H5_fold-0_Chantal, H5_fold-0_Elsa, H6_fold-C_Rei, H6_fold-Z_Gogy, H6_fold-U_Nomur, and H7_fold-K_Mussoc are presented. For each de novo designed protein, the computational model is shown on the left, ...

Northwestern Medicine investigators have solved a challenging protein design puzzle using a unique high-throughput approach, according to a study published in Proceedings of the National Academy of ...

As people around the world marveled in July at the most detailed pictures of the cosmos snapped by the James Webb Space Telescope, biologists got their first glimpses of a different set of images — ...

Programs built by Google’s artificial intelligence company DeepMind have beaten humans playing chess, Go, and some Atari computer games. Biologists and computer scientists say the company has now done ...

Computational models show that even subtle modifications in the synaptic protein CaMKII completely alter the resulting protein structures. Given how the formation and stability of these structures ...