With AI, it's now possible for researchers to predict the three-dimensional structures of proteins directly from their ...

RNA molecules exhibit an astonishing diversity in structure, which is integral to their myriad cellular functions ranging from gene regulation to catalysis. Advances in experimental techniques and ...

The field of RNA structure prediction and modeling has undergone substantial transformation in recent years, reflecting a confluence of innovative computational strategies and expanding experimental ...

Platform combines proprietary AI sequence optimization, novel genetic parts, and lab validation in application-relevant cell models to improve expression and half-life, delivering top candidates in ...

Researchers engineered the first RNA-based NAND gate in living cells using deep learning and Bayesian optimization, testing ...

RNA病毒是遗传多样性最丰富、进化速度最快的一类微生物，能够引发多种人类、动物和植物感染性疾病，对全球公共卫生与生物安全构成持续威胁。解析RNA病毒蛋白的三维结构，是理解病毒感染与免疫逃逸机制、指导抗病毒药物和疫苗研发的关键基础。然而，受限于蛋白结构解析技术等因素的限制，目前实验解析的RNA病毒蛋白结构仍然 ...

Tina de los Reyes is the strategic biopharma development specialist for the Western US. With over 10 years of commercial experience in NGS and a Masters in Biomedical diagnostics, she specializes in ...

With AI, it's now possible for researchers to predict the three-dimensional structures of proteins directly from their ...

Certain guanine-rich regions of the transcriptome can fold up into four-stranded structures called RNA G-quadruplexes that are thought to have harmful effects in living cells. Both eukaryotes and ...

When RNA molecules are synthesized by cells — a critical process in the creation of proteins and other cellular functions — they typically undergo a series of “folding” events that determine their ...

A team at UT Southwestern Medical Center has identified a structural trick that lets viruses translate their genetic code inside human cells, even when that code is riddled with “bad” codons the host ...