Spatial transcriptomics and gene expression analysis represent a transformative approach in biomedical research, integrating the spatial context of tissues with high-resolution profiling of gene ...

This figure shows how the STAIG framework can successfully identify spatial domains by integrating image processing and contrastive learning to analyze spatial transcriptomics data effectively.

Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper functioning. Understanding these spatial arrangements is important when ...

Researchers developed a new computational method to analyze complex tissue data that could transform our current understanding of diseases and how we treat them. Researchers at the University of ...

Neoadjuvant immunotherapy in combination with chemotherapy in resectable locally advanced head and neck squamous cell carcinoma: A randomized, open label, phase II clinical trial. This is an ASCO ...

Researchers at the University of Michigan and Brown University have developed a new computational method to analyze complex tissue data that could transform our current understanding of diseases and ...

Illumina is raising the curtain on its upcoming entry into spatial transcriptomics, with tech designed to help researchers explore cellular behavior mapped across complex tissues. The announcement ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Spatial transcriptomics offers a revolutionary approach to understanding the tumor microenvironment (TME) in solid tumors by preserving the spatial context of gene expression, which is crucial for ...

Breast cancer remains one of the most prevalent and life-threatening forms of cancer, impacting millions worldwide. This malignancy's heterogeneity and complexity have long posed significant ...

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...