DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

When bacteria cells replicate, they do so a little differently than human cells do. They don't undergo mitosis, a splitting that involves construction of spindles to carefully separate the DNA after ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for the ...

When bacteria cells replicate, they do so a little differently than human cells do. They don't undergo mitosis, a splitting that involves construction ...

New research shows hydroxyurea reshapes DNA replication in cancer cells, revealing stress responses that may help design ...

A team has unearthed new findings about what happens during the minutes and hours after a cell divides, expanding our understanding of human biology -- and potentially leading to better medicines. DNA ...

Mayo Clinic researchers have identified a protein that acts like a traffic controller for DNA, preventing damage during cell division - a discovery that could lead to new cancer therapies, according ...

Maize serves as a vital model species for advancing our understanding of plant biology, yet many mysteries remain about the ...